ABSTRACT
Aging is a complex, multietiological process and a major risk factor for most non-genetic, chronic diseases including geriatric syndromes that negatively affect healthspan and longevity. In the scenario of "healthy or good aging", especially during the COVID-19 era, the proper implementation of exercise as "adjuvant" or "polypill" to improve disease-related symptoms and comorbidities in the general population is a top priority. However, there is still a gap concerning studies analyzing influence of exercise training to immune system in older people. Therefore, the aim of this review is to provide a brief summary of well-established findings in exercise immunology and immunogerontology, but with a focus on the main exercise-induced mechanisms associated with aging of the immune system (immunosenescence). The scientific data strongly supports the notion that regular exercise as a low-cost and non-pharmacological treatment approach, when adjusted on an individual basis in elderly, induce multiple rejuvenating mechanisms: (1) affects the telomere-length dynamics (a "telo-protective" effect), (2) promote short- and long-term anti-inflammatory effects (via e.g., triggering the anti-inflammatory phenotype), 3) stimulates the adaptive immune system (e.g., helps to offset diminished adaptive responses) and in parallel inhibits the accelerated immunosenescence process, (4) increases post-vaccination immune responses, and (5) possibly extends both healthspan and lifespan.
ABSTRACT
There is very little research on the anthropometric and physiological profiles of lower-ranked young female athletes, even though, in most rowing clubs, such rowers constitute the vast majority. Therefore, this study investigated the anthropometric and physiological profiles of young Hungarian female rowers of different age categories and sports rankings (international vs. club). Anthropometric and physiological profiles were created for 36 junior (15–16 years), 26 older-junior (17–18 years), and 8 senior (19–21 years) female rowers who were club and international ranked members of seven of the largest Hungarian rowing clubs. Rowers >17-years-old with international rankings significantly outperformed their age-group peers with club rankings in terms of power, absolute VO2 max, and time to cover 2000 m, among other differences, but such differences were not observed with junior rowers. In all age groups, the length of the athletes’ sports career was not significantly associated with differences in anthropometric and physiological characteristics. This study suggests that ranking is not associated with differences in the anthropometric and physiological characteristics of juniors. Thus, with non-elite juniors, it can be more difficult to predict competition outcomes based on differences in anthropometric and physiological profiles.